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Skin, Hair & Cosmetic

Melanotan II

MT-II

Classification: Melanocortin receptor agonist (nonselective)

Mechanism: Nonselective agonist at MC1R/MC3R/MC4R/MC5R; stimulates melanogenesis and sexual arousal pathways

Benefits: Skin tanning; libido/erection; appetite suppression

Evidence tier: Anecdotal (Flagged Unsafe) · Availability: Research Chemical

Primary sources

  1. Wessells H et al. Melanocortin receptor agonists, penile erection, and sexual motivation — human studies with Melanotan II. Int J Impot Res 2000. PMID 11035391
  2. Nelson ME et al. Melanotan II injection resulting in systemic toxicity and rhabdomyolysis. Clin Toxicol (Phila) 2012. PMID 23121206
  3. Mang R et al. Dermoscopic changes in melanocytic nevi during use of melanotan II. Hautarzt 2012. PMID 23052015

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