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Tissue Repair & Healing

GHK

Glycyl-L-histidyl-L-lysine

Classification: Matrikine tripeptide; signaling/reparative

Mechanism: Modulates expression of hundreds of genes related to tissue repair; copper transport

Benefits: Gene modulation; tissue repair; collagen support; wound healing

Evidence tier: Preclinical + Cosmetic · Availability: Research

Primary sources

  1. Pickart L et al. The effect of the human peptide GHK on gene expression relevant to nervous system function and cognitive decline. Brain Sci 2017. PMID 28212278
  2. Maquart FX et al. In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu²⁺ in rat experimental wounds. J Clin Invest 1993. PMID 8227353

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