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Tissue Repair & Healing

BPC-157

Body Protection Compound-157; Bepecin; PL 14736

Classification: Synthetic pentadecapeptide; cytoprotective

Mechanism: Promotes angiogenesis via VEGFR2; upregulates growth factors; modulates NO and dopamine pathways; stabilizes gut barrier

Benefits: Tendon/ligament/muscle healing; gut mucosal repair; angiogenesis; reduced GI inflammation; wound healing

Evidence tier: Anecdotal + Animal Studies · Availability: Compounding Restricted

Primary sources

  1. Sikiric P et al. Stable gastric pentadecapeptide BPC 157 — review of pharmacology. Curr Pharm Des 2018. PMID 29804522
  2. Chang CH et al. The promoting effect of pentadecapeptide BPC 157 on tendon healing. J Orthop Res 2014. PMID 24375646
  3. Seiwerth S et al. Stable gastric pentadecapeptide BPC 157 and wound healing. Front Pharmacol 2021. PMID 34267654

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