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An evidence-based peptide reference
Research reference only. Not medical advice. Most compounds are not FDA-approved. These are research chemicals, not for human consumption. Consult a qualified clinician.Read methodology

Drug Class

GH-secretagogue peptides

Stimulates pituitary GH release

About the GH-secretagogue class

11 peptides on PeptideHelper.org are tagged with this class.

Class assignments are editorial; some peptides span multiple mechanism classes. Most peptides catalogued are not FDA-approved for human use.

Peptides in this class (11)

  • CJC-1295 , GHRH analog (no-DAC or DAC forms) · Anecdotal + Phase 2 (DAC) · Compounding Restricted · 57 citations
  • Ipamorelin , Growth hormone-releasing peptide (GHRP); ghrelin receptor agonist · Anecdotal + Phase 2 · Compounding Restricted · 91 citations
  • Tesamorelin , GHRH analog (FDA-approved) · FDA-Approved · Prescription · 165 citations
  • MK-677 , Oral non-peptide ghrelin receptor agonist · Phase 3 (not approved) · Research Chemical · 168 citations
  • Sermorelin , GHRH analog · Discontinued (FDA approval 1990; US withdrawal 2008) · Compounding Restricted · 247 citations
  • Hexarelin , GHRP; potent ghrelin receptor agonist · Phase 2 (not approved) · Research Chemical · 196 citations
  • GHRP-2 , GHRP; ghrelin receptor agonist · Japan-Approved Diagnostic · Research · 215 citations
  • GHRP-6 , GHRP; ghrelin receptor agonist · Anecdotal + Animal Studies · Research Chemical · 200 citations
  • CJC-1295 + Ipamorelin , GHRH analog + selective GHRP blend (GH-secretagogue stack) · Anecdotal + Animal Studies · Compounding Restricted · 6 citations
  • Tesamorelin + Ipamorelin , FDA-approved GHRH analog (Tesamorelin) + selective GHRP (Ipamorelin) blend · FDA-Approved (component) · Compounding Restricted · 2 citations
  • Hulk Stack , GH + IGF stack: GHRH analog + selective GHRP + long-acting IGF-1 analog · Anecdotal · Compounding Restricted

Frequently asked questions

What is a GH-secretagogue peptide?

Stimulates pituitary GH release

Which peptides are in the GH-secretagogue class?

11 peptides catalogued on PeptideHelper.org are tagged GH-secretagogue: CJC-1295, Ipamorelin, Tesamorelin, MK-677, Sermorelin, Hexarelin, GHRP-2, GHRP-6, CJC-1295 + Ipamorelin, Tesamorelin + Ipamorelin, Hulk Stack.

Are any GH-secretagogue peptides FDA-approved?

2 GH-secretagogue peptides are FDA-approved on PeptideHelper.org's catalog: Tesamorelin, Tesamorelin + Ipamorelin.

Browse the full PeptideHelper.org catalog with filters for evidence tier, regulatory status, and goal area.

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