PeptideHelper.org
Your evidence-based peptide reference
Research reference only. Not medical advice. Most compounds are not FDA-approved. Consult a qualified clinician before any human use.

Sexual Function & Libido

Kisspeptin-10

KP-10; metastin(45-54)

Classification: Kisspeptin receptor agonist; HPG upstream regulator

Mechanism: GPR54/KISS1R agonist on GnRH neurons; triggers LH pulse

Benefits: LH pulsatility; libido; HPG axis activation; emerging clinical use

Evidence tier: Phase 2 · Availability: Investigational

Primary sources

  1. Jayasena CN et al. The effects of kisspeptin-10 on reproductive hormone release show sexual dimorphism in humans. J Clin Endocrinol Metab 2011. PMID 21976724
  2. Patel AH et al. Kisspeptin in functional hypothalamic amenorrhea — pathophysiology and therapeutic potential. Ann N Y Acad Sci 2024. PMID 39287750

Loading interactive view…