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Growth Hormone Secretion

Follistatin

FS; FST

Classification: Myostatin-binding glycoprotein; anabolic

Mechanism: Binds and neutralizes myostatin and activin; promotes muscle growth

Benefits: Myostatin/activin inhibition; muscle hypertrophy potential

Evidence tier: Preclinical + Gene Therapy Trials · Availability: Research Chemical

Primary sources

  1. Mendell JR et al. A phase 1/2a follistatin gene therapy trial for Becker muscular dystrophy. Mol Ther 2015. PMID 25322757
  2. Amthor H et al. Follistatin complexes myostatin and antagonises myostatin-mediated inhibition of myogenesis. Dev Biol 2004. PMID 15136138

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