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Weight Loss & Metabolic

Tesofensine

NS2330

Classification: Triple monoamine reuptake inhibitor (non-peptide)

Mechanism: Inhibits reuptake of norepinephrine, dopamine, serotonin in CNS

Benefits: Weight loss ~10% Phase 2; appetite suppression

Evidence tier: Phase 2/3 (mixed) · Availability: Research Chemical

Primary sources

  1. Astrup A et al. Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients — randomised, double-blind, placebo-controlled trial. Lancet 2008. PMID 18950853

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