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Weight Loss & Metabolic

SLU-PP-332

ERRα agonist

Classification: ERR agonist small molecule (non-peptide)

Mechanism: Estrogen-related receptor (ERRα/β/γ) agonist; exercise-mimetic metabolic activation

Benefits: Exercise mimetic; endurance increase in mice; fat loss

Evidence tier: Preclinical · Availability: Experimental

Primary sources

  1. Billon C et al. Synthetic ERRα/β/γ agonist (SLU-PP-332) induces an ERRα-dependent acute aerobic exercise response and enhances exercise capacity. ACS Chem Biol 2023. PMID 36988910
  2. Billon C et al. A synthetic ERR agonist alleviates metabolic syndrome. J Pharmacol Exp Ther 2024. PMID 37739806
  3. Note: Preclinical evidence only — no published human clinical trials. Cited paper describes in-vitro or animal-model mechanism.

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