PeptideHelper.org
Your evidence-based peptide reference
Research reference only. Not medical advice. Most compounds are not FDA-approved. Consult a qualified clinician before any human use.

Weight Loss & Metabolic

5-Amino-1MQ

5-amino-1-methylquinolinium

Classification: NNMT inhibitor small molecule

Mechanism: Inhibits nicotinamide N-methyltransferase (NNMT); raises intracellular NAD+ and SAM

Benefits: NNMT inhibition; raises NAD+/SAM; fat metabolism; anti-obesity in mice

Evidence tier: Preclinical + Anecdotal · Availability: Research Chemical

Primary sources

  1. Dimet-Wiley A et al. Reduced calorie diet combined with NNMT inhibition (5-amino-1MQ) establishes a distinct microbiome in DIO mice. Sci Rep 2022. PMID 35013352

Loading interactive view…